Hemophilia Essay -- essays research papers fc

Hemophilia is the oldest known hereditary bleed disorder. at that place are two types of haemophilia, A and B (Christmas Disease). Low levels or fetch up absence of a inception protein essential for turn causes both. Patients with hemophilia A leave out the blood clotting protein, factor VIII, and those with hemophilia B lack factor IX. A mortal with tremendous hemophilia has less than 1% of the normal get of a clotting factor - either component part VIII (8) or Factor IX (9). People without hemophilia engender between 50-150% of the normal level of factor VIII or IX. there are around 20,000 hemophilia patients in the United States. Each year, about 400 babies are born with this disorder. Approximately 85% shake up hemophilia A and the remainder has hemophilia B. The severity of hemophilia is related to the amount of the clotting factor in the blood. About 70% of hemophilia patients have less than one percent of the normal amount and, thus, have severe hemophilia. A sm solely increase in the blood level of the clotting factor, up to five percent of normal, results in lowly hemophilia with grand bleeding except after injuries or surgery.This is not a chore when a person with hemophilia has a simple cut or scrape. He doesnt bleed any faster than the average person. He can hold pressure on the cut and platelets in the blood will stop the bleeding.The problem for people with hemophilia is bleeding inner the body, especially bleeding into joints like the knees, elbows, and ankles. When bleeding happens inside the joint, it becomes very swollen-headed and painful. Repeated bleeding into a joint can cause a type of crippling arthritis. Bleeding inside other parts of the body, much(prenominal) as the brain, throat, and abdomen can be life-threatening. A person with mild hemophilia may only have problems with bleeding when he has surgery, major(ip) dental work, or a severe injury. A person with crack hemophilia will have those problems plus bleedin g problems with more humble injuries such as a hard bump to the knee. A person with severe hemophilia can have what are called spontaneous bleeds - bleeding that starts inside the body for no known reason.Hemophilia is classified as mild, moderate or severe, depending on the amount of clotting factor a person has in his body. Severe hemophilia is actually the most universal form. People with hemophilia are born with the disorder and have it all of their lives. You cant ca... ...ed HIV.Factor VIII gene is characterized and cloned. 1985Viral-inactivated factor concentrates become available.ELISA and Hesperian Blot Test are developed to test antibodies for HIV.1989Hepatitis C virus, previously called non-A, non-B, is set.1991Testing for hepatitis C is introduced.1992 set-back recombinant factor VIII products become available.1995First case of variant Creutzfeldt-Jakob disease, the human form of Mad Cow disease, is identified in the U.K.1997First recombinant factor IX products bec ome available.1998Gene therapy trials on humans begin.Effective treatment for hemophilia is available, but as however there is no cure. Bleeding can be treated with an shooting of clotting factor that is made from blood or biotechnological ingredients called recombinants. Bleeding shekels when enough clotting factor reaches the affected area. Works CitedI.Principles Of Genetics seventh Edition, Robert H. Tamarin. 2002II.World Federation of Hemophilia. www.wfh.orgIII.Hemophilia of Georgia. www.hog.orgIV.Hemophilia Village. Hemophiliavillage.com